Expression of Cytokine Receptors by Human Cord Blood Lymphocytes: Comparison with Adult Blood Lymphocytes
نویسندگان
چکیده
منابع مشابه
Intracellular Cytokine Profiles of Cord and Adult Blood Lymphocytes
important genetic-environmental interaction. Blood 91:4158, 1998 2. Jacques PF, Bostom AG, Williams RR, Ellison RC, Eckfeldt JH, Rosenberg IH, Selhub J, Rozen R: Relation between folate status, a common mutation in methylenetetrahydrofolate reductase, and plasma homocysteine concentrations. Circulation 93:7, 1996 3. Verhoef P, Kok FJ, Kluijtmans LAJ, Blom HJ, Refsum H, Ueland PM, Kruyssen DACM:...
متن کاملIntracellular cytokine profiles of cord and adult blood lymphocytes.
important genetic-environmental interaction. Blood 91:4158, 1998 2. Jacques PF, Bostom AG, Williams RR, Ellison RC, Eckfeldt JH, Rosenberg IH, Selhub J, Rozen R: Relation between folate status, a common mutation in methylenetetrahydrofolate reductase, and plasma homocysteine concentrations. Circulation 93:7, 1996 3. Verhoef P, Kok FJ, Kluijtmans LAJ, Blom HJ, Refsum H, Ueland PM, Kruyssen DACM:...
متن کاملIntracellular cytokine profile of cord and adult blood lymphocytes.
Umbilical cord blood (CB) transplantation is thought to be associated with a reduced risk of severe graft-versus-host-disease (GVHD) compared with bone marrow transplantation (BMT). The cytokine cascade is known to be important in the pathogenesis of GVHD; however, previous studies investigating the cytokine secretion pattern of CB cells have been contradictory because of variations in experime...
متن کاملCord blood T lymphocytes lack constitutive perforin expression in contrast to adult peripheral blood T lymphocytes.
Perforin is the cytolytic pore-forming protein, which alone can be responsible for the lethal hit in one of the killing mechanisms used by natural killer (NK) cells or cytotoxic T lymphocytes. In this study, perforin expression was investigated in cord blood (CB) lymphocytes to determine their killing potential in vivo. The majority of CB CD3- NK cells had the protein. Compared with adult perfo...
متن کاملEx vivo expansion of human umbilical cord blood-derived T-lymphocytes with homologous cord blood plasma.
This study was designed to establish a more effective and safe culture system for adoptive immunotherapy by investigating the use of homologous cord blood plasma (HCBP) instead of fetal bovine serum (FBS), which has various limitations including ethical problems for the ex vivo expansion of human umbilical T lymphocytes. Fresh human umbilical mononuclear cell fractions were isolated by Ficoll-H...
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ژورنال
عنوان ژورنال: Pediatric Research
سال: 1995
ISSN: 0031-3998,1530-0447
DOI: 10.1203/00006450-199509000-00021